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\/>\n\u4e09\u3001\u9002\u7528\u4eba\u7fa4\u4e0e\u7981\u5fcc\u4eba\u7fa4\uff1a\u8c01\u80fd\u5403\uff1f\u8c01\u7edd\u5bf9\u4e0d\u80fd\u5403\uff1f<br \/>\n\uff08\u4e00\uff09\u9002\u7528\u4eba\u7fa4\uff08\u56fd\u5185\u83b7\u6279\u6838\u5fc3\u573a\u666f\uff09<br \/>\n1. \u00a0\u4e0e2\u578b\u7cd6\u5c3f\u75c5\u76f8\u5173\u7684\u6162\u6027\u80be\u810f\u75c5\u6210\u4eba\u60a3\u8005\uff0c\u4e14\u80be\u5c0f\u7403\u6ee4\u8fc7\u7387\u4f30\u8ba1\u503c\uff08eGFR\uff09\u226525\u81f3\uff1c75 mL\/min\/1.73\u33a1\uff0c\u4f34\u767d\u86cb\u767d\u5c3f\uff1b<br \/>\n2. \u00a0\u5c04\u8840\u5206\u6570\u4fdd\u7559\u7684\u5fc3\u529b\u8870\u7aed\u60a3\u8005\uff08\u8fd1\u5e74\u6765\u65b0\u589e\u9002\u5e94\u75c7\uff09\u3002<br \/>\n\u8865\u5145\u8bf4\u660e\uff1a\u975e\u7cd6\u5c3f\u75c5\u80be\u75c5\u3001\u513f\u7ae5\u60a3\u8005\u3001eGFR\uff1c25 mL\/min\/1.73\u33a1\u7684\u4e25\u91cd\u80be\u529f\u80fd\u4e0d\u5168\u60a3\u8005\uff0c\u76ee\u524d\u4e0d\u63a8\u8350\u4f7f\u7528\u3002<br \/>\n\uff08\u4e8c\uff09\u7981\u5fcc\u4eba\u7fa4\uff08\u7edd\u5bf9\u4e0d\u80fd\u4f7f\u7528\uff09<br \/>\n1. \u00a0\u5bf9\u975e\u5948\u5229\u916e\u6216\u5176\u8f85\u6599\u8fc7\u654f\u8005\uff1b<br \/>\n2. \u00a0\u4e0eCYP3A4\u5f3a\u6548\u6291\u5236\u5242\u8054\u5408\u7528\u836f\u8005\uff08\u5982\u4f0a\u66f2\u5eb7\u5511\u3001\u916e\u5eb7\u5511\u3001\u514b\u62c9\u9709\u7d20\u3001\u5229\u6258\u90a3\u97e6\u7b49\uff09\uff1b<br \/>\n3. \u00a0\u60a3\u6709\u827e\u8fea\u751f\u75c5\uff08Addison\u6c0f\u75c5\uff09\u8005\uff1b<br \/>\n4. \u00a0\u91cd\u5ea6\u80be\u529f\u80fd\u635f\u5bb3\u3001\u7ec8\u672b\u671f\u80be\u75c5\u6216\u6b63\u5728\u63a5\u53d7\u900f\u6790\u6cbb\u7597\u7684\u60a3\u8005\uff1b<br \/>\n5. \u00a0\u6025\u6027\u6216\u6162\u6027\u809d\u75c5\u3001\u809d\u529f\u80fd\u635f\u5bb3\uff08\u5982\u8f6c\u6c28\u9176\u5347\u9ad8\uff09\u7684\u60a3\u8005\uff1b<br \/>\n6. \u00a0\u598a\u5a20\u671f\u3001\u54fa\u4e73\u671f\u5973\u6027\u3002<br \/>\n\u56db\u3001\u79d1\u5b66\u7528\u836f\u6307\u5357\uff1a\u7528\u6cd5\u3001\u5242\u91cf\u4e0e\u76d1\u6d4b\u91cd\u70b9<br \/>\n\u975e\u5948\u5229\u916e\u7684\u7528\u836f\u6838\u5fc3\u662f\u201c\u4e2a\u4f53\u5316\u5242\u91cf\u3001\u5b9a\u671f\u76d1\u6d4b\u201d\uff0c\u64c5\u81ea\u670d\u7528\u6216\u8c03\u6574\u5242\u91cf\u53ef\u80fd\u589e\u52a0\u4e0d\u826f\u53cd\u5e94\u98ce\u9669\uff0c\u4ee5\u4e0b\u91cd\u70b9\u5185\u5bb9\u52a1\u5fc5\u7262\u8bb0\uff1a<br \/>\n\uff08\u4e00\uff09\u7528\u6cd5\u7528\u91cf<br \/>\n1. \u00a0\u7ed9\u836f\u65b9\u5f0f\uff1a\u53e3\u670d\uff0c\u53ef\u4e0e\u98df\u7269\u540c\u670d\u6216\u7a7a\u8179\u670d\u7528\uff0c\u5efa\u8bae\u6bcf\u5929\u5728\u540c\u4e00\u65f6\u95f4\u670d\u7528\uff08\u63a8\u8350\u65e9\u6668\u670d\u7528\uff09\uff0c\u65b9\u4fbf\u8bb0\u5fc6\uff1b<br \/>\n2. \u00a0\u8d77\u59cb\u5242\u91cf\uff1a\u6839\u636e\u60a3\u8005\u7684eGFR\u6c34\u5e73\u786e\u5b9a\uff1a<br \/>\n&#8211; eGFR\u226560 mL\/min\/1.73\u33a1\uff1a\u8d77\u59cb\u5242\u91cf20mg\uff0c\u6bcf\u65e51\u6b21\uff1b<br \/>\n&#8211; eGFR\u226525\u81f3\uff1c60 mL\/min\/1.73\u33a1\uff1a\u8d77\u59cb\u5242\u91cf10mg\uff0c\u6bcf\u65e51\u6b21\uff1b<br \/>\n3. \u00a0\u5242\u91cf\u8c03\u6574\uff1a\u76ee\u6807\u5242\u91cf\u4e3a20mg\uff0c\u6bcf\u65e51\u6b21\u3002\u5f00\u59cb\u6cbb\u7597\u540e4\u5468\u5185\u68c0\u6d4b\u8840\u94be\u6c34\u5e73\uff0c\u6839\u636e\u8840\u94be\u7ed3\u679c\u8c03\u6574\u5242\u91cf\uff1a<br \/>\n&#8211; \u8840\u94be\u22644.8 mmol\/L\uff1a\u53ef\u5c06\u5242\u91cf\u8c03\u6574\u81f320mg\uff0c\u6bcf\u65e51\u6b21\uff1b<br \/>\n&#8211; \u8840\u94be4.8~5.0 mmol\/L\uff1a\u7ef4\u6301\u5f53\u524d\u5242\u91cf\uff0810mg\uff09\uff0c\u6bcf\u65e51\u6b21\uff1b<br \/>\n&#8211; \u8840\u94be\uff1e5.5 mmol\/L\uff1a\u6682\u505c\u6cbb\u7597\uff0c\u5f85\u8840\u94be\u22645.0 mmol\/L\u540e\uff0c\u53ef\u8003\u8651\u91cd\u65b0\u5f00\u59cb\uff0c\u5242\u91cf\u4e3a10mg\uff0c\u6bcf\u65e51\u6b21\uff1b<br \/>\n4. \u00a0\u6f0f\u670d\u5904\u7406\uff1a\u53d1\u73b0\u6f0f\u670d\u540e\u5c3d\u5feb\u670d\u7528\uff0c\u4f46\u4ec5\u5728\u6f0f\u670d\u5f53\u5929\u8865\u670d\uff1b\u82e5\u5df2\u5230\u7b2c\u4e8c\u5929\uff0c\u76f4\u63a5\u8df3\u8fc7\u8be5\u5242\u91cf\uff0c\u6309\u539f\u8ba1\u5212\u670d\u7528\u4e0b\u4e00\u5242\u91cf\uff0c\u5207\u52ff\u4e00\u6b21\u670d\u7528\u4e24\u500d\u5242\u91cf\uff1b<br \/>\n5. \u00a0\u7279\u6b8a\u670d\u7528\uff1a\u65e0\u6cd5\u541e\u54bd\u6574\u7247\u7247\u5242\u7684\u60a3\u8005\uff0c\u53ef\u5728\u7528\u836f\u524d\u5c06\u836f\u7247\u538b\u788e\uff0c\u4e0e\u6c34\u6216\u8f6f\u98df\uff08\u5982\u82f9\u679c\u9171\uff09\u6df7\u5408\u540e\u7acb\u5373\u53e3\u670d\u3002<br \/>\n\uff08\u4e8c\uff09\u76d1\u6d4b\u91cd\u70b9<br \/>\n1. \u00a0\u7528\u836f\u524d\uff1a\u5fc5\u987b\u68c0\u6d4b\u8840\u94be\u548ceGFR\uff0c\u82e5\u8840\u94be\uff1e5.0 mmol\/L\uff0c\u7981\u6b62\u5f00\u59cb\u6cbb\u7597\uff1b<br \/>\n2. \u00a0\u7528\u836f\u671f\u95f4\uff1a\u5f00\u59cb\u6cbb\u7597\u6216\u8c03\u6574\u5242\u91cf\u540e4\u5468\u5185\uff0c\u590d\u67e5\u8840\u94be\u548ceGFR\uff1b\u7a33\u5b9a\u540e\uff0c\u81f3\u5c11\u6bcf3~4\u4e2a\u6708\u76d1\u6d4b\u4e00\u6b21\uff1b<br \/>\n3. \u00a0\u9ad8\u98ce\u9669\u4eba\u7fa4\uff1aeGFR\u8f83\u4f4e\u3001\u65e2\u5f80\u6709\u9ad8\u94be\u8840\u75c7\u75c5\u53f2\u7684\u60a3\u8005\uff0c\u9700\u66f4\u9891\u7e41\u5730\u76d1\u6d4b\u8840\u94be\u3002<br \/>\n\u4e94\u3001\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\u4e0e\u6ce8\u610f\u4e8b\u9879<br \/>\n\uff08\u4e00\uff09\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\uff08\u591a\u4e3a\u8f7b\u5ea6\uff0c\u53ef\u8010\u53d7\uff09<br \/>\n1. \u00a0\u9ad8\u94be\u8840\u75c7\uff1a\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\uff0c\u53d1\u751f\u7387\u7ea614%\uff0c\u4f4e\u4e8e\u4f20\u7edfMRA\u7c7b\u836f\u7269\uff0c\u8868\u73b0\u4e3a\u4e4f\u529b\u3001\u5fc3\u60b8\u3001\u808c\u8089\u65e0\u529b\u7b49\uff0c\u4e00\u65e6\u51fa\u73b0\u9700\u53ca\u65f6\u5c31\u533b\uff1b<br \/>\n2. \u00a0\u80c3\u80a0\u9053\u53cd\u5e94\uff1a\u8f7b\u5ea6\u6076\u5fc3\u3001\u8179\u6cfb\u3001\u4fbf\u79d8\u7b49\uff0c\u591a\u5728\u7528\u836f\u521d\u671f\u51fa\u73b0\uff0c\u968f\u6cbb\u7597\u8fdb\u5c55\u4f1a\u9010\u6e10\u51cf\u8f7b\uff1b<br \/>\n3. \u00a0\u8840\u538b\u53d8\u5316\uff1a\u90e8\u5206\u60a3\u8005\u53ef\u80fd\u51fa\u73b0\u8f7b\u5ea6\u8840\u538b\u964d\u4f4e\uff0c\u5c24\u5176\u662f\u5408\u5e76\u4f7f\u7528\u5176\u4ed6\u964d\u538b\u836f\u65f6\uff0c\u9700\u6ce8\u610f\u76d1\u6d4b\u8840\u538b\uff1b<br \/>\n4. \u00a0\u5176\u4ed6\uff1a\u5c11\u6570\u4eba\u53ef\u80fd\u51fa\u73b0\u76ae\u75b9\u3001\u7619\u75d2\u7b49\u8fc7\u654f\u53cd\u5e94\uff0c\u6216\u8f6c\u6c28\u9176\u5347\u9ad8\u7b49\u809d\u529f\u80fd\u5f02\u5e38\uff0c\u9700\u53ca\u65f6\u544a\u77e5\u533b\u751f\u3002<br \/>\n\uff08\u4e8c\uff09\u5173\u952e\u6ce8\u610f\u4e8b\u9879<br \/>\n1. \u00a0\u996e\u98df\u7981\u5fcc\uff1a\u670d\u836f\u671f\u95f4\uff0c\u907f\u514d\u98df\u7528\u8461\u8404\u67da\u6216\u996e\u7528\u8461\u8404\u67da\u6c41\uff0c\u56e0\u4e3a\u8461\u8404\u67da\u4f1a\u6291\u5236\u836f\u7269\u4ee3\u8c22\uff0c\u589e\u52a0\u4e0d\u826f\u53cd\u5e94\u98ce\u9669\uff1b\u9ad8\u94be\u8840\u75c7\u98ce\u9669\u8f83\u9ad8\u8005\uff0c\u9700\u91c7\u53d6\u4f4e\u94be\u996e\u98df\uff0c\u51cf\u5c11\u9999\u8549\u3001\u725b\u6cb9\u679c\u3001\u8c46\u7c7b\u3001\u575a\u679c\u7b49\u9ad8\u94be\u98df\u7269\u7684\u6444\u5165\uff1b<br \/>\n2. \u00a0\u836f\u7269\u8054\u7528\u7981\u5fcc\uff1a\u7981\u6b62\u4e0e\u4fdd\u94be\u5229\u5c3f\u5242\uff08\u5982\u963f\u7c73\u6d1b\u5229\u3001\u6c28\u82ef\u8776\u5576\uff09\u3001\u5176\u4ed6\u76d0\u76ae\u8d28\u6fc0\u7d20\u53d7\u4f53\u62ee\u6297\u5242\uff08\u5982\u87ba\u5185\u916f\u3001\u4f9d\u666e\u5229\u916e\uff09\u8054\u7528\uff0c\u907f\u514d\u52a0\u91cd\u9ad8\u94be\u8840\u75c7\uff1b\u8054\u7528\u4e2d\u6548\u6216\u5f31\u6548CYP3A\u6291\u5236\u5242\u65f6\uff0c\u9700\u52a0\u5f3a\u8840\u94be\u76d1\u6d4b\uff1b<br \/>\n3. \u00a0\u7279\u6b8a\u4eba\u7fa4\uff1a\u8001\u5e74\u4eba\u4e00\u822c\u65e0\u9700\u8c03\u6574\u5242\u91cf\uff0c\u4f46\u9700\u52a0\u5f3a\u8840\u94be\u548c\u80be\u529f\u80fd\u76d1\u6d4b\uff1b\u4e2d\u5ea6\u809d\u529f\u80fd\u635f\u5bb3\u60a3\u8005\u9700\u989d\u5916\u76d1\u6d4b\u8840\u94be\uff0c\u91cd\u5ea6\u809d\u529f\u80fd\u635f\u5bb3\u60a3\u8005\u7981\u6b62\u4f7f\u7528\uff1b<br \/>\n4. \u00a0\u505c\u836f\u6307\u5f81\uff1a\u8840\u94be\uff1e5.5 mmol\/L\u3001\u51fa\u73b0\u80be\u4e0a\u817a\u529f\u80fd\u4e0d\u5168\u75c7\u72b6\u65f6\uff0c\u9700\u7acb\u5373\u6682\u505c\u7528\u836f\uff1b\u8fdb\u5c55\u81f3\u7ec8\u672b\u671f\u80be\u75c5\uff08eGFR\uff1c15 mL\/min\/1.73\u33a1\uff09\u7684\u60a3\u8005\uff0c\u5e94\u505c\u6b62\u6cbb\u7597\u3002<br \/>\n\u516d\u3001\u603b\u7ed3\uff1a\u7406\u6027\u770b\u5f85\uff0c\u79d1\u5b66\u4f7f\u7528<br \/>\n\u975e\u5948\u5229\u916e\u7684\u51fa\u73b0\uff0c\u4e3a2\u578b\u7cd6\u5c3f\u75c5\u76f8\u5173\u6162\u6027\u80be\u810f\u75c5\u3001\u5c04\u8840\u5206\u6570\u4fdd\u7559\u7684\u5fc3\u529b\u8870\u7aed\u60a3\u8005\u5e26\u6765\u4e86\u65b0\u7684\u6cbb\u7597\u5e0c\u671b\uff0c\u5176\u201c\u5fc3\u80be\u53cc\u62a4\u201d\u7684\u4f18\u52bf\u7684\u7684\u4f20\u7edf\u836f\u7269\u96be\u4ee5\u66ff\u4ee3[8]\u3002\u4f46\u5b83\u5e76\u975e\u201c\u4e07\u80fd\u836f\u201d\uff0c\u4e5f\u4e0d\u662f\u4eba\u4eba\u9002\u7528\uff0c\u6838\u5fc3\u662f\u201c\u7cbe\u51c6\u5339\u914d\u4eba\u7fa4\u3001\u4e25\u683c\u9075\u533b\u5631\u7528\u836f\u3001\u5b9a\u671f\u76d1\u6d4b\u201d\u3002<br \/>\n\u6700\u540e\u63d0\u9192\u5927\u5bb6\uff1a\u975e\u5948\u5229\u916e\u5c5e\u4e8e\u5904\u65b9\u836f\uff0c\u5fc5\u987b\u5728\u533b\u751f\u6216\u836f\u5e08\u7684\u6307\u5bfc\u4e0b\u4f7f\u7528\uff0c\u5207\u52ff\u81ea\u884c\u8d2d\u4e70\u3001\u8c03\u6574\u5242\u91cf\u6216\u505c\u836f\uff1b\u7528\u836f\u671f\u95f4\uff0c\u52a1\u5fc5\u505a\u597d\u76d1\u6d4b\uff0c\u53ca\u65f6\u6c9f\u901a\u8eab\u4f53\u4e0d\u9002\uff0c\u624d\u80fd\u6700\u5927\u5316\u53d1\u6325\u836f\u7269\u7597\u6548\uff0c\u89c4\u907f\u5b89\u5168\u98ce\u9669\u3002<br \/>\n\u5982\u679c\u8eab\u8fb9\u67092\u578b\u7cd6\u5c3f\u75c5\u5408\u5e76\u80be\u75c5\u3001\u5fc3\u529b\u8870\u7aed\u7684\u4eb2\u53cb\uff0c\u4e0d\u59a8\u628a\u8fd9\u7bc7\u6587\u7ae0\u8f6c\u7ed9\u4ed6\u4eec\uff0c\u4e00\u8d77\u79d1\u5b66\u5b88\u62a4\u5fc3\u80be\u5065\u5eb7\uff5e<br \/>\n\ufffc<br \/>\n\u4e00\u3001\u975e\u5948\u5229\u916e\u4eff\u5236\u836f\u5e02\u573a\u73b0\u72b6<br 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