{"id":739,"date":"2023-12-28T19:09:34","date_gmt":"2023-12-28T11:09:34","guid":{"rendered":"http:\/\/www.yaozhiyou.com\/?p=739"},"modified":"2023-12-28T19:09:34","modified_gmt":"2023-12-28T11:09:34","slug":"furmonertinib-%e4%bc%8f%e7%be%8e%e6%9b%bf%e5%b0%bc-%e8%89%be%e5%bc%97%e6%b2%99","status":"publish","type":"post","link":"https:\/\/www.yaozhiyou.com\/?p=739","title":{"rendered":"Furmonertinib \u4f0f\u7f8e\u66ff\u5c3c \u827e\u5f17\u6c99"},"content":{"rendered":"
\"Furmonertinib

Furmonertinib \u4f0f\u7f8e\u66ff\u5c3c \u827e\u5f17\u6c99<\/p><\/div>\n

\u836f\u54c1\u6982\u8ff0<\/h3>\n
\n

\u827e\u5f17\u6c99(\u4f0f\u7f8e\u66ff\u5c3c)Furmonertinib\uff0c\u7814\u53d1\u4ee3\u7801AST2818\uff0c\u66fe\u7528\u540d\u827e\u6c1f\u66ff\u5c3c(alflutinib)\uff0c\u662f\u7b2c3\u4ee3\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242(EGFR-TKI)\u3002
<\/p>\n

2021\u5e743\u67083\u65e5\uff0c\u4e2d\u56fd\u56fd\u5bb6\u5c40\u5b98\u7f51\u663e\u793a\uff0c\u827e\u529b\u65af\u533b\u836f\u7684\u7532\u78fa\u9178\u4f0f\u7f8e\u66ff\u5c3c\u5df2\u83b7NMPA\u6279\u51c6\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597EGFR T790M\u7a81\u53d8\u9633\u6027\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c<\/a>(NSCLC)\u3002

2022\u5e746\u670828\u65e5\uff0c\u4f0f\u7f8e\u66ff\u5c3c\u65b0\u9002\u5e94\u75c7\u5df2\u83b7\u5f97\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u6279\u51c6\uff0c\u7528\u4e8e\u5177\u6709\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u5916\u663e\u5b5019\u7f3a\u5931\uff0819DEL\uff09\u6216\u5916\u663e\u5b5021\uff08L858R\uff09\u7f6e\u6362\u7a81\u53d8\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c<\/a>\uff08NSCLC\uff09\u6210\u4eba\u60a3\u8005\u7684\u4e00\u7ebf\u6cbb\u7597<\/strong>\u3002<\/p>\n<\/div>\n

\u7b80\u8981\u8bf4\u660e\u4e66<\/h3>\n
\n\n\n\n\n\n\n\n\n
Furmonertinib\u00a0\u4f0f\u7f8e\u66ff\u5c3c(\u827e\u5f17\u6c99\u00ae)<\/strong>\u8bf4\u660e\u4e66<\/strong><\/td>\n<\/tr>\n
\u836f\u7269\uff1a<\/td>\nFurmonertinib\u00a0\u7532\u78fa\u9178\u4f0f\u7f8e\u66ff\u5c3c\u7247(\u827e\u5f17\u6c99\u00ae)<\/td>\n<\/tr>\n
\u4e2d\u56fd\u4e0a\u5e02\uff1a<\/td>\n\u5df2\u4e0a\u5e02<\/td>\n<\/tr>\n
\u6cbb\u7597\uff1a<\/td>\n\u7528\u4e8e\u6cbb\u7597EGFR\u654f\u611f\u7a81\u53d8\u53caEGFRT790M\u8010\u836f\u7a81\u53d8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c(NSCLC)\u3002<\/td>\n<\/tr>\n
\u53c2\u8003\u7528\u6cd5\u7528\u91cf\uff1a<\/td>\n\u53e3\u670d,\u6bcf\u65e5\u4e00\u6b21\uff0c\u6bcf\u6b212\u7247\u3002<\/td>\n<\/tr>\n
\u4e0d\u826f\u53cd\u5e94\uff1a<\/td>\n\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94\u5305\u62ec\u8f6c\u6c28\u9176\u5347\u9ad8\u3001\u4e0a\u547c\u5438\u9053\u611f\u67d3\u3001\u54b3\u55fd(\u53d1\u751f\u7387\u5747\u572815%\u5de6\u53f3)\u3002\u8179\u6cfb\u7684\u53d1\u751f\u7387\u8f83\u4f4e(6.0%)\uff0c\u22653\u7ea7\u7684\u8179\u6cfb\u4e3a0.4%\u300219.1%\u7684\u60a3\u8005\u53d1\u751f\u4e863-5\u7ea7AE\uff0c\u6700\u5e38\u89c1\u7684\u662f\u03b3-\u8c37\u6c28\u9170\u8f6c\u79fb\u9176\u5347\u9ad8(n=4)\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\u54a8\u8be2\u8ddf\u591a\uff0c \u8bf7\u5fae\uff1alkhong77<\/h3>\n","protected":false},"excerpt":{"rendered":"

\u836f\u54c1\u6982\u8ff0 \u827e\u5f17\u6c99(\u4f0f\u7f8e\u66ff\u5c3c)Furmonertinib\uff0c\u7814\u53d1\u4ee3\u7801AST2818\uff0c\u66fe\u7528\u540d\u827e\u6c1f\u66ff\u5c3c(alflutinib)\uff0c\u662f\u7b2c3\u4ee3\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242(EGFR-TKI)\u3002 2021\u5e743\u67083\u65e5\uff0c\u4e2d\u56fd\u56fd\u5bb6\u5c40\u5b98\u7f51\u663e\u793a\uff0c\u827e\u529b\u65af\u533b\u836f\u7684\u7532\u78fa […]<\/p>\n","protected":false},"author":1,"featured_media":740,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12],"tags":[274,275,276],"topic":[],"class_list":["post-739","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-feiaiyaoping","tag-furmonertinib","tag-275","tag-276"],"_links":{"self":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/739","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=739"}],"version-history":[{"count":1,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/739\/revisions"}],"predecessor-version":[{"id":741,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/739\/revisions\/741"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/media\/740"}],"wp:attachment":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=739"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=739"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=739"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftopic&post=739"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}