{"id":359,"date":"2023-10-10T15:34:44","date_gmt":"2023-10-10T07:34:44","guid":{"rendered":"http:\/\/www.yaozhiyou.com\/?p=359"},"modified":"2023-10-19T18:35:44","modified_gmt":"2023-10-19T10:35:44","slug":"%e9%98%bf%e5%9f%b9%e5%88%a9%e5%8f%b8","status":"publish","type":"post","link":"https:\/\/www.yaozhiyou.com\/?p=359","title":{"rendered":"\u963f\u57f9\u5229\u53f8"},"content":{"rendered":"\n<figure class=\"wp-block-image size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"263\" height=\"300\" src=\"https:\/\/www.yaozhiyou.com\/wp-content\/uploads\/2023\/10\/53-263x300.jpg\" alt=\"\u963f\u57f9\u5229\u53f8\" class=\"wp-image-360\" srcset=\"https:\/\/www.yaozhiyou.com\/wp-content\/uploads\/2023\/10\/53-263x300.jpg 263w, https:\/\/www.yaozhiyou.com\/wp-content\/uploads\/2023\/10\/53.jpg 720w\" sizes=\"auto, (max-width: 263px) 100vw, 263px\" \/><\/figure>\n\n\n\n<p>\u963f\u57f9\u5229\u53f8(Alpelisib,BYL719,PIQRAY) \u7531\u8bfa\u534e\u516c\u53f8\u7814\u53d1\uff0c\u8be5\u836f\u4e8e2019\u5e745\u670824\u65e5\u83b7\u5f97\u7f8e\u56fdFDA\u6279\u51c6\u4e0a\u5e02,\u662fFDA\u6279\u51c6\u7684\u9996\u4e2a\u78f7\u8102\u9170\u808c\u91873\u6fc0\u9176( PI3K)\u6291\u5236\u5242,\u5546\u54c1\u540d\u4e3aPiqray\u3002<br>PIQRAY\u9002\u7528\u4e8e\u4e0e\u6c1f\u7ef4\u53f8\u7fa4\u8054\u5408\u6cbb\u7597\u7edd\u7ecf\u540e\u5987\u5973\u548c\u7537\u6027\uff0c\u6fc0\u7d20\u53d7\u4f53(HR)\u9633\u6027\u3001\u4eba\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f532 (HER2)\u9634\u6027\u3001PIK3CA\u7a81\u53d8\u3001\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c\uff0c\u5728\u57fa\u4e8e\u5185\u5206\u6ccc\u7684\u6cbb\u7597\u65b9\u6848\u8fdb\u5c55\u540e\u6216\u4e4b\u540e\u901a\u8fc7FDA\u6279\u51c6\u7684\u68c0\u6d4b\u8fdb\u884c\u68c0\u6d4b\u3002<br>\u963f\u57f9\u5229\u53f8\u9002\u7528\u9776\u70b9<br>\u963f\u57f9\u5229\u53f8\u7684\u4f5c\u7528\u9776\u70b9\u662fPIK3CA\u3002<\/p>\n\n\n\n<p>\u963f\u57f9\u5229\u53f8\u7528\u6cd5\u7528\u91cf<br>1\u3001\u60a3\u8005\u9009\u62e9<br>\u6839\u636e\u80bf\u7624\u7ec4\u7ec7\u6216\u8840\u6d46\u6807\u672c\u4e2d\u662f\u5426\u5b58\u5728\u4e00\u79cd\u6216\u591a\u79cdPIK3CA\u7a81\u53d8\uff0c\u9009\u62e9\u63a5\u53d7PIQRAY\u6cbb\u7597\u7684HR\u9633\u6027\u3001HER2\u9634\u6027\u665a\u671f\u6216\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u60a3\u8005\u3002\u5982\u679c\u8840\u6d46\u6807\u672c\u4e2d\u672a\u68c0\u6d4b\u5230\u7a81\u53d8\uff0c\u5219\u68c0\u6d4b\u80bf\u7624\u7ec4\u7ec7\u3002<br>2\u3001\u5242\u91cf\u548c\u7528\u6cd5<br>PIQRAY\u7684\u63a8\u8350\u5242\u91cf\u4e3a300 mg(\u4e24\u7247150 mg\u8584\u819c\u5305\u8863\u7247\u5242)\uff0c\u968f\u98df\u7269\u53e3\u670d\uff0c\u6bcf\u65e5\u4e00\u6b21\u3002\u7ee7\u7eed\u6cbb\u7597\uff0c\u76f4\u81f3\u51fa\u73b0\u75be\u75c5\u8fdb\u5c55\u6216\u4e0d\u53ef\u63a5\u53d7\u7684\u6bd2\u6027\u3002\u60a3\u8005\u5e94\u5728\u6bcf\u5929\u5927\u81f4\u76f8\u540c\u7684\u65f6\u95f4\u670d\u7528\u5176\u5242\u91cf\u7684PIQRAY\u3002<br>\u5c06PIQRAY\u836f\u7247\u6574\u7c92\u541e\u4e0b(\u836f\u7247\u5728\u541e\u54bd\u524d\u4e0d\u5e94\u5480\u56bc\u3001\u538b\u788e\u6216\u88c2\u5f00)\u3002\u5982\u679c\u836f\u7247\u7834\u635f\u3001\u88c2\u5f00\u6216\u4ee5\u5176\u4ed6\u65b9\u5f0f\u4e0d\u5b8c\u6574\uff0c\u5219\u4e0d\u5e94\u5c06\u5176\u6444\u5165\u3002\u5982\u679c\u9519\u8fc7\u4e86PIQRAY\u7684\u67d0\u4e2a\u5242\u91cf\uff0c\u53ef\u5728\u901a\u5e38\u670d\u836f\u65f6\u95f4\u540e9\u5c0f\u65f6\u5185\u4e0e\u98df\u7269\u540c\u670d\u3002\u8d85\u8fc79\u5c0f\u65f6\u540e\uff0c\u8df3\u8fc7\u5f53\u5929\u7684\u5242\u91cf\u3002\u7b2c\u4e8c\u5929\uff0c\u5728\u901a\u5e38\u65f6\u95f4\u670d\u7528PIQRAY\u3002<\/p>\n\n\n\n<p>\u5982\u679c\u60a3\u8005\u5728\u670d\u7528\u8be5\u5242\u91cf\u540e\u5455\u5410\uff0c\u5219\u5efa\u8bae\u60a3\u8005\u5f53\u5929\u4e0d\u8981\u670d\u7528\u989d\u5916\u5242\u91cf\uff0c\u5e76\u5728\u7b2c\u4e8c\u5929\u7684\u6b63\u5e38\u65f6\u95f4\u6062\u590d\u7ed9\u836f\u8ba1\u5212\u3002<\/p>\n\n\n\n<p>\u5f53\u4e0ePIQRAY\u8054\u5408\u7528\u836f\u65f6\uff0c\u6c1f\u7ef4\u53f8\u7fa4\u7684\u63a8\u8350\u5242\u91cf\u4e3a\u7b2c1\u300115\u548c29\u5929\u670d\u7528500 mg\uff0c\u4e4b\u540e\u6bcf\u6708\u4e00\u6b21\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u963f\u57f9\u5229\u53f8(Alpelisib,BYL719,PIQRAY) \u7531\u8bfa\u534e\u516c\u53f8\u7814\u53d1\uff0c\u8be5\u836f\u4e8e2019\u5e745\u670824\u65e5\u83b7\u5f97\u7f8e\u56fdFDA\u6279\u51c6\u4e0a\u5e02,\u662fFDA\u6279\u51c6\u7684\u9996\u4e2a\u78f7\u8102\u9170\u808c\u91873\u6fc0\u9176( PI3K)\u6291\u5236\u5242,\u5546\u54c1\u540d\u4e3aPiqray\u3002PIQRAY\u9002\u7528\u4e8e\u4e0e\u6c1f\u7ef4\u53f8\u7fa4\u8054\u5408\u6cbb\u7597 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":360,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[137,136,135],"topic":[],"class_list":["post-359","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ruxianluanchao","tag-pik3ca","tag-136","tag-135"],"_links":{"self":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/359","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=359"}],"version-history":[{"count":2,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/359\/revisions"}],"predecessor-version":[{"id":379,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/359\/revisions\/379"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/media\/360"}],"wp:attachment":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=359"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=359"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=359"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftopic&post=359"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}