{"id":341,"date":"2023-10-10T12:43:55","date_gmt":"2023-10-10T04:43:55","guid":{"rendered":"http:\/\/www.yaozhiyou.com\/?p=341"},"modified":"2023-10-19T18:37:59","modified_gmt":"2023-10-19T10:37:59","slug":"%e5%88%a9%e4%bc%90%e6%b2%99%e7%8f%ad%e7%89%87xarelto%e6%8b%9c%e7%91%9e%e5%a6%a5rivaroxaban","status":"publish","type":"post","link":"https:\/\/www.yaozhiyou.com\/?p=341","title":{"rendered":"\u5229\u4f10\u6c99\u73ed\u7247Xarelto(\u62dc\u745e\u59a5rivaroxaban)"},"content":{"rendered":"\n
\"\u5229\u4f10\u6c99\u73ed\u7247Xarelto(\u62dc\u745e\u59a5rivaroxaban)\"<\/figure>\n\n\n\n

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  \u62fc\u97f3\u5168\u7801\uff1aLiFaShaBanPian(BaiRuiTuo)<\/p>\n\n\n\n

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   \u5206\u5b50\u91cf\uff1aC19H18ClN3O5S<\/p>\n\n\n\n

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mg\uff0c\u6bcf\u65e5\u4e24\u6b21[bid])\u5408\u7528\u65f6\uff0c\u5229\u4f10\u6c99\u73ed\u7684\u5e73\u5747AUC\u5347\u9ad8\u4e862.6\u500d\/2.5\u500d\uff0c\u5229\u4f10\u6c99\u73ed\u7684\u5e73\u5747Cmax\u5347\u9ad8\u4e861.7\u500d\/1.6\u500d,\u540c\u65f6\u836f\u6548\u663e\u8457\u63d0\u9ad8\uff0c\u53ef\u80fd\u5bfc\u81f4\u51fa\u8840\u98ce\u9669\u5347\u9ad8\u3002\u56e0\u6b64\uff0c\u4e0d\u5efa\u8bae\u5c06\u5229\u4f10\u6c99\u73ed\u4e0e\u5421\u54af-\u6297\u771f\u83cc\u5242(\u4f8b\u5982\u916e\u5eb7\u5511\u3001\u4f0a\u66f2\u5eb7\u5511\u3001\u4f0f\u7acb\u5eb7\u5511\u548c\u6cca\u6c99\u5eb7\u5511)\u6216HIV\u86cb\u767d\u9176\u6291\u5236\u5242\u5168\u8eab\u7528\u836f\u65f6\u5408\u7528\u3002\u8fd9\u4e9b\u6d3b\u6027\u7269\u8d28\u662fCYP3A4\u548cP\u2013gp\u7684\u5f3a\u6548\u6291\u5236\u5242\u3002\u9884\u8ba1\u6c1f\u5eb7\u5511\u5bf9\u4e8e\u5229\u4f10\u6c99\u73ed\u8840\u836f\u6d53\u5ea6\u7684\u5f71\u54cd\u8f83\u5c0f\uff0c\u53ef\u4ee5\u8c28\u614e\u5730\u5408\u5e76\u7528\u836f\u3002 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