{"id":326,"date":"2023-10-09T15:12:11","date_gmt":"2023-10-09T07:12:11","guid":{"rendered":"http:\/\/www.yaozhiyou.com\/?p=326"},"modified":"2023-10-20T17:00:13","modified_gmt":"2023-10-20T09:00:13","slug":"%e5%8d%b0%e5%ba%a6%e4%bc%8f%e7%ab%8b%e5%ba%b7%e5%94%91voriconazole","status":"publish","type":"post","link":"https:\/\/www.yaozhiyou.com\/?p=326","title":{"rendered":"\u4f0f\u7acb\u5eb7\u5511(Voriconazole)"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"400\" height=\"400\" src=\"https:\/\/www.yaozhiyou.com\/wp-content\/uploads\/2023\/10\/41.jpg\" alt=\"\u4f0f\u7acb\u5eb7\u5511\" class=\"wp-image-327\" srcset=\"https:\/\/www.yaozhiyou.com\/wp-content\/uploads\/2023\/10\/41.jpg 400w, https:\/\/www.yaozhiyou.com\/wp-content\/uploads\/2023\/10\/41-300x300.jpg 300w, https:\/\/www.yaozhiyou.com\/wp-content\/uploads\/2023\/10\/41-150x150.jpg 150w\" sizes=\"auto, (max-width: 400px) 100vw, 400px\" \/><\/figure>\n\n\n\n<p>\u4f0f\u7acb\u5eb7\u5511\uff08\u6210\u4eba\uff09<\/p>\n\n\n\n<p>\u5242\u578b<br>\u53e3\u670d\u6db2 \u4e3a200\u6beb\u514b\/ 5\u6beb\u5347<br>\u6ce8\u5c04\u7528\u7c89\u672b \u4e3a200mg<br>\u7247\u5242 \u4e3a50mg\u3001200mg<br><br>\u4fb5\u88ad\u6027\u66f2\u9709\u83cc\u75c5<br>\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5927\u591a\u6570\u56de\u6536\u7684\u83cc\u682a\u662f\u70df\u66f2\u9709\uff08Aspergillus fumigatus\uff09<\/p>\n\n\n\n<p>\u524d24\u5c0f\u65f6 \u9759\u8109\u6ce8\u5c046mg \/ kg \u6bcf12\u5c0f\u65f6\u9759\u8109\u6ce8\u5c041\u6b21<\/p>\n\n\n\n<p>\u7136\u540e \u6bcf12\u5c0f\u65f6\u9759\u8109\u6ce8\u5c04 4mg \/ kg<\/p>\n\n\n\n<p>\u6216<\/p>\n\n\n\n<p>\u6bcf12\u5c0f\u65f6\/1\u6b21 \u53e3\u670d &nbsp;200mg<\/p>\n\n\n\n<p>\u4e2d\u4f4d\u6cbb\u7597\u65f6\u95f4\uff1a\u9759\u8109\u6ce8\u5c0410\u5929\uff082-90\u5929\uff09; \u53e3\u670d 76\u5929\uff08\u8303\u56f42-232\u5929\uff09<\/p>\n\n\n\n<p>\u5ff5\u73e0\u83cc<br>\u5176\u4ed6\u6df1\u90e8\u7ec4\u7ec7\u5ff5\u73e0\u83cc\u611f\u67d3\u7684\u975e\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\u60a3\u8005\uff08\u5982\u767d\u8272\u5ff5\u73e0\u83cc\uff0c\u5149\u6ed1\u5ff5\u73e0\u83cc\uff0c\u514b\u9c81\u65af\u5ff5\u73e0\u83cc\uff0c\u8fd1\u5e73\u6ed1\u5ff5\u73e0\u83cc\uff0c\u70ed\u5e26\u5047\u4e1d\u9175\u6bcd\uff09\u8868\u660e\u5ff5\u73e0\u83cc\u8840\u75c7<\/p>\n\n\n\n<p>\u524d6\u5c0f\u65f6 \u9759\u8109\u6ce8\u5c04 6 mg \/ kg<\/p>\n\n\n\n<p>\u7136\u540e \u6bcf12\u5c0f\u65f6 \u9759\u8109\u6ce8\u5c04 3-4 mg \/ kg<\/p>\n\n\n\n<p>\u6216 \u6bcf12\u5c0f\u65f6\/1\u6b21 \u53e3\u670d 200 mg<\/p>\n\n\n\n<p>\u98df\u9053\u5ff5\u73e0\u83cc\u75c5<br>\u767d\u8272\u5ff5\u73e0\u83cc\uff0c\u5149\u6ed1\u5ff5\u73e0\u83cc\uff0c\u514b\u9c81\u6c0f\u5047\u4e1d\u9175\u6bcd\u83cc<\/p>\n\n\n\n<p>200\u6beb\u514b \u53e3\u670d \u6bcf12\u5c0f\u65f6\/1\u6b21<\/p>\n\n\n\n<p>\u4e25\u91cd\u7684\u771f\u83cc\u611f\u67d3<br>\u7531Scedosporium apiospermum\uff08\u65e0\u6027\u5f62\u5f0f\u7684Pseudallescheria boydii\uff09\u548cFusarium spp\u5f15\u8d77\u3002\u5305\u62ec\u9570\u5200\u83cc\uff08Fusarium solani\uff09\uff0c\u60a3\u8005\u5bf9\u5176\u4ed6\u6cbb\u7597\u4e0d\u8010\u53d7\u6216\u96be\u4ee5\u6cbb\u7597<\/p>\n\n\n\n<p>\u524d24\u5c0f\u65f6\u9759\u8109\u6ce8\u5c046mg \/ kg<\/p>\n\n\n\n<p>\u7136\u540e\u6bcf12\u5c0f\u65f6\uff0c\u9759\u8109\u6ce8\u5c044mg \/ kg<\/p>\n\n\n\n<p>\u6216 200mg \u53e3\u670d \u6bcf12\u5c0f\u65f6\/1\u6b21<\/p>\n\n\n\n<p>\u5242\u91cf\u8c03\u6574<br>\u4f53\u91cd&lt;40 mg\u7684\u6210\u4eba\uff1a\u53e3\u670d\u7ef4\u6301\u5242\u91cf\u51cf\u5c1150\uff05<\/p>\n\n\n\n<p>\u80be\u529f\u80fd\u635f\u5bb3\uff08CrCl &lt;50 mL \/ min\uff09\uff1a\u4ec5\u4f7f\u7528\u53e3\u670d\u5f62\u5f0f\u8fdb\u884c\u7ef4\u6301; \u7531\u4e8eIV\u8f7d\u4f53\uff08SBECD\uff09\u7684\u7d2f\u79ef\u800c\u907f\u514dIV\u7ed9\u836f<\/p>\n\n\n\n<p>\u809d\u529f\u80fd\u635f\u5bb3<\/p>\n\n\n\n<p>\u8f7b\u5ea6\u4e2d\u5ea6\uff08Child-Pugh A\u6216B\uff09\uff1a\u7ed9\u4e88\u6807\u51c6\u8d1f\u8377\u5242\u91cf\uff0c\u4f46\u7ef4\u6301\u5242\u91cf\u51cf\u5c1150\uff05<br>\u4e25\u91cd\uff08Child-Pugh C\uff09\uff1a\u65e0\u53ef\u7528\u6570\u636e<br>\u4e59\u578b\u809d\u708e\u6216\u4e19\u578b\u809d\u708e\uff1a\u65e0\u53ef\u7528\u6570\u636e<br>\u53cd\u5e94\u4e0d\u8db3<\/p>\n\n\n\n<p>\u5c06\u53e3\u670d\u7ef4\u6301\u5242\u91cf\u4ece200mg \u6bcf12\u5c0f\u65f6\/1\u6b21\u589e\u52a0\u81f3300mg \u53e3\u670d \u6bcf12\u5c0f\u65f6\/1\u6b21<br>&lt;40 kg\uff1a\u5c06\u53e3\u670d\u7ef4\u6301\u5242\u91cf\u4ece100 mg \u6bcf12\u5c0f\u65f6\/1\u6b21\u589e\u52a0\u81f3150 mg \u6bcf12\u5c0f\u65f6\/1\u6b21<br>\u7ba1\u7406<br>\u57281-2\u5c0f\u65f6\u5185\u76ae\u4e0b\u6ce8\u5c04\uff0c\u4e0d\u8d85\u8fc73\u6beb\u514b\/\u5343\u514b\/\u5c0f\u65f6<\/p>\n\n\n\n<p>\u5728\u9910\u524d\u6216\u9910\u540e1\u5c0f\u65f6\u670d\u7528\u53e3\u670d\u5242<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f0f\u7acb\u5eb7\u5511\uff08\u6210\u4eba\uff09 \u5242\u578b\u53e3\u670d\u6db2 \u4e3a200\u6beb\u514b\/ 5\u6beb\u5347\u6ce8\u5c04\u7528\u7c89\u672b \u4e3a200mg\u7247\u5242 \u4e3a50mg\u3001200mg \u4fb5\u88ad\u6027\u66f2\u9709\u83cc\u75c5\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u5927\u591a\u6570\u56de\u6536\u7684\u83cc\u682a\u662f\u70df\u66f2\u9709\uff08Aspergillus fumigatus\uff09 \u524d24\u5c0f\u65f6 \u9759\u8109\u6ce8\u5c046mg \/ k [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":327,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28],"tags":[148],"topic":[],"class_list":["post-326","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-xijunbd","tag-148"],"_links":{"self":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/326","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=326"}],"version-history":[{"count":3,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/326\/revisions"}],"predecessor-version":[{"id":452,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/326\/revisions\/452"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/media\/327"}],"wp:attachment":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=326"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=326"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=326"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftopic&post=326"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}