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\"\"<\/figure>\n\n\n\n


\u3000\u3000\u3010\u9002\u5e94\u8bc1\u548c\u7528\u9014\u3011<\/p>\n\n\n\n

\u3000\u3000\u5c3c\u8fbe\u5c3c\u5e03\u662f\u4e00\u79cd\u6fc0\u9176\u6291\u5236\u5242\u9002\u7528\u4e3a\u7279\u53d1\u6027\u80ba\u7ea4\u7ef4\u5316(IPF)\u7684\u6cbb\u7597\u3002<\/p>\n\n\n\n

\u3000\u3000\u3010\u5242\u91cf\u548c\u7ed9\u836f\u65b9\u6cd5\u3011<\/p>\n\n\n\n

\u3000\u3000\u2474 \u63a8\u8350\u5242\u91cf\uff1a150 mg\u6bcf\u59292\u6b21\u95f4\u9694\u7ea612\u5c0f\u65f6\u4e0e\u98df\u7269\u670d\u7528\u3002<\/p>\n\n\n\n

\u3000\u3000\u2475 \u8003\u8651\u6682\u65f6\u5242\u91cf\u51cf\u4f4e\u81f3100 mg\uff0c\u6cbb\u7597\u4e2d\u65ad\uff0c\u6216\u7ec8\u6b62\u4e3a\u5904\u7406\u4e0d\u826f\u53cd\u5e94\u3002<\/p>\n\n\n\n

\u3000\u3000\u2476 \u6cbb\u7597\u524d\uff0c\u8fdb\u884c\u809d\u529f\u80fd\u68c0\u9a8c\u3002<\/p>\n\n\n\n

\u3000\u3000\u3010\u5242\u578b\u548c\u89c4\u683c\u3011<\/p>\n\n\n\n

\u3000\u3000\u80f6\u56ca\uff1a150 mg\u548c100 mg<\/p>\n\n\n\n

\u3000\u3000\u3010\u7981\u5fcc\u8bc1\u3011<\/p>\n\n\n\n

\u3000\u3000\u65e0<\/p>\n\n\n\n

\u3000\u3000\u3010\u8b66\u544a\u548c\u6ce8\u610f\u4e8b\u9879\u3011<\/p>\n\n\n\n

\u3000\u3000\u2474 \u809d\u9176\u5347\u9ad8\uff1a\u7528\u5c3c\u8fbe\u5c3c\u5e03\u66fe\u53d1\u751fALT\uff0cAST\uff0c\u548c\u80c6\u7ea2\u7d20\u5347\u9ad8\u3002\u6cbb\u7597\u524d\u548c\u671f\u95f4\u76d1\u89c6ALT\uff0cAST\uff0c\u548c\u80c6\u7ea2\u7d20\u3002\u53ef\u80fd\u9700\u8981\u6682\u65f6\u51cf\u4f4e\u5242\u91cf\u6216\u7ec8\u6b62\u3002<\/p>\n\n\n\n

\u3000\u3000\u2475 \u80c3\u80a0\u9053\u75be\u75c5\uff1a\u7528\u5c3c\u8fbe\u5c3c\u5e03\u66fe\u53d1\u751f\u8179\u6cfb\uff0c\u6076\u5fc3\uff0c\u548c\u5455\u5410\u3002\u7b2c\u4e00\u4e2a\u5f81\u8c61\u7528\u5145\u5206\u6c34\u5316\u548c\u6b62\u6cfb\u836f(\u5982\uff0c\u6d1b\u54cc\u4e01\u80fa[loperamide])\u6216\u6297\u5410\u836f\u6cbb\u7597\u60a3\u8005\u3002\u5982\u5c3d\u7ba1\u5bf9\u75c7\u6cbb\u7597\u4e25\u91cd\u8179\u6cfb\uff0c\u6076\u5fc3\uff0c\u6216\u5455\u5410\u6301\u7eed\u7ec8\u6b62\u5c3c\u8fbe\u5c3c\u5e03\u3002<\/p>\n\n\n\n

\u3000\u3000\u2476 \u80da\u80ce\u80ce\u513f\u6bd2\u6027\uff1a\u5e94\u529d\u544a\u80b2\u9f84\u5987\u5973\u5bf9\u80ce\u513f\u6f5c\u5728\u5371\u5bb3\u548c\u907f\u514d\u6210\u4e3a\u598a\u5a20\u3002<\/p>\n\n\n\n

\u3000\u3000\u2477 \u66fe\u62a5\u9053\u52a8\u8109\u8840\u6813\u6813\u585e\u4e8b\u4ef6\u3002\u5f53\u6cbb\u7597\u60a3\u8005\u5904\u4e8e\u8f83\u9ad8\u5fc3\u8840\u7ba1\u98ce\u9669\u5305\u62ec\u5df2\u77e5\u51a0\u72b6\u52a8\u8109\u75be\u75c5\u8c28\u614e\u4f7f\u7528\u3002<\/p>\n\n\n\n

\u3000\u3000\u2478 \u66fe\u62a5\u9053\u51fa\u8840\u4e8b\u4ef6\u3002\u53ea\u6709\u5df2\u77e5\u51fa\u8840\u98ce\u9669\u60a3\u8005\u671f\u671b\u83b7\u76ca\u80dc\u8fc7\u6f5c\u5728\u98ce\u9669\u65f6\u4f7f\u7528FEV\u3002<\/p>\n\n\n\n

\u3000\u3000\u2479 \u66fe\u62a5\u9053\u80c3\u80a0\u9053\u7a7f\u5b54\u3002\u6700\u8fd1\u8179\u90e8\u624b\u672f\u6cbb\u7597\u60a3\u8005\u8c28\u614e\u4f7f\u7528\u5c3c\u8fbe\u5c3c\u5e03\u3002\u53d1\u751f\u80c3\u80a0\u9053\u7a7f\u5b54\u60a3\u8005\u7ec8\u6b62\u5c3c\u8fbe\u5c3c\u5e03\u3002\u53ea\u6709\u6709\u5df2\u77e5\u80c3\u80a0\u9053\u7a7f\u5b54\u98ce\u9669\u5982\u671f\u671b\u83b7\u76ca\u80dc\u8fc7\u6f5c\u5728\u98ce\u9669\u624d\u4f7f\u7528\u5c3c\u8fbe\u5c3c\u5e03\u3002<\/p>\n\n\n\n

\u3000\u3000\u3010\u4e0d\u826f\u53cd\u5e94\u3011<\/p>\n\n\n\n

\u3000\u3000\u6700\u5e38\u89c1\u4e0d\u826f\u53cd\u5e94(\u22655%)\u662f\uff1a\u8179\u6cfb\uff0c\u6076\u5fc3\uff0c\u8179\u75db\uff0c\u5455\u5410\uff0c\u809d\u9176\u5347\u9ad8\uff0c\u98df\u6b32\u51cf\u9000\uff0c\u5934\u75db\uff0c\u4f53\u91cd\u51cf\u8f7b\uff0c\u548c\u9ad8\u8840\u538b\u3002<\/p>\n\n\n\n

\u3000\u3000\u836f\u7269\u76f8\u4e92\u4f5c\u7528<\/p>\n\n\n\n

\u3000\u3000P-gp\u548cCYP3A4\u6291\u5236\u5242\u5171\u540c\u7ed9\u836f\u53ef\u80fd\u589e\u52a0nintedanib\u66b4\u9732\u3002\u5bc6\u5207\u76d1\u89c6\u60a3\u8005\u5bf9\u5c3c\u8fbe\u5c3c\u5e03\u8010\u53d7\u6027\u3002<\/p>\n\n\n\n

\u3000\u3000\u3010\u7279\u6b8a\u4eba\u7fa4\u4e2d\u4f7f\u7528\u3011<\/p>\n\n\n\n

\u3000\u3000\u2474 \u54fa\u4e73\u6bcd\u4eb2\uff1a\u7ec8\u6b62\u54fa\u4e73\u6216\u7ec8\u6b62\u836f\u7269\uff0c\u8003\u8651\u836f\u7269\u5bf9\u6bcd\u4eb2\u91cd\u8981\u6027\u3002<\/p>\n\n\n\n

\u3000\u3000\u2475 \u809d\u53d7\u635f\uff1a\u5bf9\u6709\u8f7b\u5ea6\u809d\u53d7\u635f\u60a3\u8005\u76d1\u89c6\u4e0d\u826f\u53cd\u5e94\u548c\u9700\u8981\u65f6\u8003\u8651\u8c03\u6574\u5242\u91cf\u6216\u7ec8\u6b62\u5c3c\u8fbe\u5c3c\u5e03\u3002\u6709\u4e2d\u5ea6\u6216\u4e25\u91cd\u809d\u53d7\u635f\u60a3\u8005\u4e2d\u4e0d\u5efa\u8bae\u4f7f\u7528\u5c3c\u8fbe\u5c3c\u5e03\u3002<\/p>\n\n\n\n

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\u3000\u3000\u3010\u9002\u5e94\u8bc1\u548c\u7528\u9014\u3011 \u3000\u3000\u5c3c\u8fbe\u5c3c\u5e03\u662f\u4e00\u79cd\u6fc0\u9176\u6291\u5236\u5242\u9002\u7528\u4e3a\u7279\u53d1\u6027\u80ba\u7ea4\u7ef4\u5316(IPF)\u7684\u6cbb\u7597\u3002 \u3000\u3000\u3010\u5242\u91cf\u548c\u7ed9\u836f\u65b9\u6cd5\u3011 \u3000\u3000\u2474 \u63a8\u8350\u5242\u91cf\uff1a150 mg\u6bcf\u59292\u6b21\u95f4\u9694\u7ea612\u5c0f\u65f6\u4e0e\u98df\u7269\u670d\u7528\u3002 \u3000\u3000\u2475 \u8003\u8651\u6682\u65f6\u5242\u91cf\u51cf\u4f4e\u81f3100 mg\uff0c\u6cbb\u7597\u4e2d\u65ad\uff0c\u6216\u7ec8\u6b62\u4e3a\u5904 […]<\/p>\n","protected":false},"author":1,"featured_media":131,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12],"tags":[],"topic":[],"class_list":["post-130","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-feiaiyaoping"],"_links":{"self":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/130","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=130"}],"version-history":[{"count":1,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/130\/revisions"}],"predecessor-version":[{"id":132,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/posts\/130\/revisions\/132"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=\/wp\/v2\/media\/131"}],"wp:attachment":[{"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=130"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=130"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=130"},{"taxonomy":"topic","embeddable":true,"href":"https:\/\/www.yaozhiyou.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftopic&post=130"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}