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\"\u683c\u5217\u536b\uff08\u4f0a\u9a6c\u66ff\u5c3c\uff09\"<\/figure>\n\n\n\n

\u3010\u9002\u5e94\u75c7\u3011<\/p>\n\n\n\n

\u3000\u3000\u7528\u4e8e\u6cbb\u7597\u6162\u6027\u7c92\u7ec6\u80de\u767d\u8840\u75c5(CML)\u6025\u53d8\u671f\u3001\u52a0\u901f\u671f\u6216\u03b1-\u5e72\u6270\u7d20\u6cbb\u7597\u5931\u8d25\u540e\u7684\u6162\u6027\u671f\u60a3\u8005\u3002<\/p>\n\n\n\n

\u3000\u3000\u7528\u4e8e\u6cbb\u7597\u4e0d\u80fd\u5207\u9664\u548c\/\u6216\u53d1\u751f\u8f6c\u79fb\u7684\u6076\u6027\u80c3\u80a0\u9053\u95f4\u8d28\u80bf\u7624\uff08GIST\uff09\u7684\u6210\u4eba\u60a3\u8005\u3002<\/p>\n\n\n\n

\u3000\u3000\u3010\u7528\u6cd5\u7528\u91cf\u3011<\/p>\n\n\n\n

\u3000\u3000\u672c\u54c1\u5e94\u53e3\u670d\uff0c\u5b9c\u5728\u8fdb\u9910\u65f6\u670d\u836f\uff0c\u5e76\u996e\u4e00\u5927\u676f\u6c34\u3002\u901a\u5e38\u6210\u4eba\u6bcf\u65e5\u4e00\u6b21\u3002<\/p>\n\n\n\n

\u3000\u3000\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u6bcf\u65e5\u4e00\u6b21\u6216\u5206\u4e24\u6b21\u670d\u7528\uff08\u65e9\u6668\u548c\u665a\u4e0a\uff09\u3002<\/p>\n\n\n\n

\u3000\u3000\u4e0d\u80fd\u541e\u54bd\u7247\u5242\u7684\u75c5\u4eba\uff08\u513f\u7ae5\uff09\uff0c\u53ef\u4ee5\u5c06\u7247\u5242\u5206\u6563\u4e8e\u6c34\u6216\u82f9\u679c\u6c41\u4e2d\u3002<\/p>\n\n\n\n

\u3000\u3000\u5efa\u8bae\u6000\u5b55\u671f\u548c\u54fa\u4e73\u671f\u5987\u5973\u5728\u6253\u5f00\u80f6\u56ca\u65f6\uff0c\u907f\u514d\u836f\u7269\u4e0e\u76ae\u80a4\u6216\u773c\u775b\u63a5\u89e6\uff0c\u6216\u8005\u5438\u5165\uff08\u89c1\u5b55\u5987\u548c\u54fa\u4e73\u671f\u5987\u5973\uff09\uff0c\u63a5\u89e6\u6253\u5f00\u7684\u80f6\u56ca\u540e\u5e94\u7acb\u5373\u6d17\u624b\u3002<\/p>\n\n\n\n

\u3000\u3000\u3010\u6ce8\u610f\u4e8b\u9879\u3011<\/p>\n\n\n\n

\u3000\u3000\u5927\u7ea6\u67091-2%\u670d\u7528\u7532\u78fa\u9178\u4f0a\u9a6c\u66ff\u5c3c\u7684\u60a3\u8005\u53d1\u751f\u4e25\u91cd\u6c34\u6f74\u7559\uff08\u80f8\u6c34\u3001\u6d6e\u80bf\u3001\u80ba\u6c34\u80bf\u548c\u8179\u6c34\uff09\uff0c\u56e0\u6b64\u5efa\u8bae\u5b9a\u671f\u76d1\u6d4b\u4f53\u91cd\uff0c\u5982\u7528\u836f\u8fc7\u7a0b\u4e2d\u4f53\u91cd\u51fa\u4e4e\u610f\u6599\u5730\u5feb\u901f\u589e\u52a0\uff0c\u5e94\u4f5c\u8be6\u7ec6\u68c0\u67e5\uff0c\u5fc5\u8981\u65f6\u91c7\u53d6\u9002\u5f53\u652f\u6301\u6cbb\u7597\u548c\u5904\u7406\u63aa\u65bd\u3002<\/p>\n\n\n\n

\u3000\u3000\u6c34\u6f74\u7559\u53ef\u4ee5\u52a0\u91cd\u6216\u5bfc\u81f4\u5fc3\u8870\uff0c\u5c1a\u65e0\u4e25\u91cd\u5fc3\u8870\u8005\uff08\u6309\u7ebd\u7ea6\u5fc3\u810f\u5b66\u4f1a\u5206\u7c7b\u6cd5\u7684III-IV\u7ea7\uff09\u4e34\u5e8a\u5e94\u7528\u7532\u78fa\u9178\u4f0a\u9a6c\u66ff\u5c3c\u7684\u7ecf\u9a8c\u3002\u5bf9\u8fd9\u4e9b\u60a3\u8005\u7528\u672c\u836f\u8981\u8c28\u614e\u3002\u809d\u529f\u80fd\u8870\u7aed\u60a3\u8005\u7532\u78fa\u9178\u4f0a\u9a6c\u66ff\u5c3c\u7684\u91cf\u53ef\u80fd\u4f1a\u589e\u52a0\uff0c\u6709\u809d\u529f\u635f\u5bb3\u8005\u614e\u7528\u672c\u836f\u3002<\/p>\n\n\n\n

\u3000\u3000\u6709\u5173\u672c\u836f\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u7684\u957f\u671f\u4e34\u5e8a\u8d44\u6599\u5c1a\u6709\u9650\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u8868\u660e\uff0c\u7532\u78fa\u9178\u4f0a\u9a6c\u66ff\u5c3c\u4e0d\u6613\u901a\u8fc7\u8840\u8111\u5c4f\u969c\u3002\u5c1a\u672a\u5728\u4eba\u4f53\u8fdb\u884c\u8fc7\u7814\u7a76\u3002\u7532\u78fa\u9178\u4f0a\u9a6c\u66ff\u5c3c\u6cbb\u7597\u7b2c1\u4e2a\u6708\u5b9c\u6bcf\u5468\u67e51\u6b21\u5168\u8840\u8c61\uff0c\u7b2c2\u4e2a\u6708\u6bcf2\u5468\u67e51\u6b21\uff0c\u4ee5\u540e\u5219\u89c6\u9700\u8981\u800c\u5b9a\uff08\u5982\u6bcf2\uff0d3\u4e2a\u6708\u67e51\u6b21\uff09\u3002\u82e5\u53d1\u751f\u4e25\u91cd\u4e2d\u6027\u7c92\u7ec6\u80de\u6216\u8840\u5c0f\u677f\u51cf\u5c11\uff0c\u5e94\u8c03\u6574\u5242\u91cf\u3002\u5f00\u59cb\u6cbb\u7597\u524d\u5e94\u68c0\u67e5\u809d\u529f\u80fd\uff08\u5305\u62ec\u8f6c\u6c28\u9176\u3001\u80c6\u7ea2\u8d28\u548c\u78b1\u6027\u78f7\u9178\u9176\uff09\uff0c\u968f\u540e\u6bcf\u6708\u67e51\u6b21\u6216\u6839\u636e\u4e34\u5e8a\u60c5\u51b5\u51b3\u5b9a\uff0c\u5fc5\u8981\u65f6\u5b9c\u8c03\u6574\u5242\u91cf\u3002\u5bf9\u9a7e\u9a76\u5458\u548c\u673a\u5668\u64cd\u7eb5\u8005\u80fd\u529b\u7684\u5f71\u54cd\u5c1a\u65e0\u6709\u5173\u5bf9\u9a7e\u9a76\u5458\u6216\u673a\u5668\u64cd\u7eb5\u8005\u80fd\u529b\u53ef\u80fd\u53d1\u751f\u7684\u5f71\u54cd\u7684\u4fe1\u606f\u548c\u8d44\u6599\u3002<\/p>\n\n\n\n

\u3000\u3000\u3010\u4e0d\u826f\u53cd\u5e94\u53ca\u7981\u5fcc\u3011<\/p>\n\n\n\n

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\u3000\u3000\u3010\u7981\u5fcc\u3011<\/p>\n\n\n\n

\u3000\u3000\u5bf9 imatinib (\u4f0a\u9a6c\u66ff\u5c3c) \u8d85\u654f\u611f\u7684\u60a3\u8005\u662f\u7981\u6b62\u4f7f\u7528\u3002<\/p>\n\n\n\n

\u3000\u3000\u5b55\u5987\u7528\u836f\uff1a<\/p>\n\n\n\n

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\u3000\u3000\u513f\u7ae5\u7528\u836f\uff1a<\/p>\n\n\n\n

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\u3000\u3000\u3010\u8d2e\u85cf\u3011<\/p>\n\n\n\n

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